Program draft ver. 1.7. Jul 20th, 2015
Industrial Biotechnology for Lignocellulose Based Processes -Course ProgramSunday October 25th Introduction, raw material composition and sources
Title N.1 By Room LO KS101 9:00-‐9:45 Course introduction. Round the table presentations 9:45-‐10:00 Coffee Bioethanol and the development towards the concept of 1 LO KS101 10:00-‐10:45 biorefinery – an overview Plant cell wall fundamentals and chemical structure of 2 2 TBA KS101 10:45-‐12:00 plant cell wall material 12:00-‐13:00 Lunch 3 LO KS101 13:00-‐14:15 Cellulolytic enzymes 4 MG KS101 14:15-‐15:00 Pretreatment methods 15:00-‐15:30 Coffee 5 EA KS101 15:30-‐16:15 Algal biomass in a biorefinery perspective Basic raw material analytics: HPLC, HPAEC, reducing 6 LO KS101 16:15-‐16:45 sugars 16:45-‐17:30 Exercise and discussion KS101 Dinner & Student poster presentation and get-together Fakultetsvåningen Time
Monday October 26th Characterization of lignocelluloses and their pretreatment and enzymatic hydrolysis Time
9:00-‐9:45 9:50-‐10:30 10:30-‐10:45 10:50-‐12:00 12:00-‐13:00 13:00-‐13:30
Title Enzymatic hydrolysis of lignocellulose Business aspects in biorefinery development Coffee Exercise and discussion Lunch The challenges of measuring cellulolytic activities-‐ discussion
I
Room KSJ KS101 KSJ KS101 KSJ KS101
9
KSJ
N. 7 8
By
KS101
Program draft ver. 1.7. Jul 20th, 2015 Monday October 26 th -continued Time Title
N.
By
13:30-‐14:00 Enzyme classification and the CAZY database
10
KSJ
14:05-‐14:55 Enzyme discovery for biorefinery applications
11
JL
12
CC
Room KS101 KS101 KS101
KSJ/JL
KS101
N.
By
Room
13
TBA
KS101
14:55-‐15:30 Coffee 15:30-‐16:30 Bioenergy and biomaterials sustainability issues 16:30-‐18:00
Exercise and discussion on enzyme classification and discovery
18:00-‐19:30 Dinner 19:30-‐ Time for further discussions and individual study
Tuesday October, 27th Enzymes and their action Time
Title Challenges in sample preparation and analysis of 09:00-‐10:00 lignocellulose polymeric materials 10:00-‐10:15 Coffee 10:15-‐11:00 Advanced hemicellulose analysis 11:05-‐12:00 Mannanolytic enzymes 12:00-‐13:00 Lunch 13:00-‐14:15 Xylanolytic enzymes 14:15-‐15:00 Carbohydrates from algae 15:00-‐15:15 Coffee The challenges of measuring hemicellulytic activities: 15:15-‐16:15 lecture and discussion 16:15-‐17:00 Exercise and discussion Course Dinner downtown Gothenburg M/S Marieholm
14 15 16 17
FVD KS101 KBK KS101 10:an KBK KS101 EA/JVV KS101
18 KBK/JL
KS101 KS101 KS101
N.
By
19
JL
Room KS101
20
CJF
KS101
21
LO
KS101
22
MB
KS101
23
MB
KS101
Wednesday October 28th Microorganisms Time 9:00-‐10:00 10:00-‐10:15 10:15-‐11:00 11:00-‐12:00 12:00-‐13:00 13:00-‐13:45 13:50-‐14:30
Title Bacterial anaerobic degradation of cellulose Coffee Different products of microbial metabolism and thermodynamic driving forces Enzyme production by filamentous fungi: from secretion to large scale production Lunch Inhibitors in lignocellulose hydrolysates Strain improvement by mutagenesis, directed evolution and metabolic engineering II
Program draft ver. 1.7. Jul 20th, 2015 W ednesday October 28 th -continued Time Title 14:30-‐15:00 Coffee 15:00-‐15:30 15:35-‐16:30 16:30-‐17:15 17:15-‐18:15 18:15-‐20:00 20:00-‐
Strain improvement by mutagenesis, directed evolution and metabolic engineering-‐ continued Development of industrial yeast strains Cell propagation Exercises and discussion Pizza at the department and lab visit Facultative night exercise and question time
N.
By
Room
23
MB
KS101
24
TBA
25
LO
MB
KS101 KS101 KS101
N.
By
Room
26
CJF
KS101
26
CJF
KS101
27
KH
KS101
28
TBA
KS101
29
DM
KS101
30
MB
KS101
KS101
Thursday October 29th Fermentation processes Time 9:00-‐10:00 10:00-‐10:15 10:15-‐11:00 11:00-‐12:00 12:00-‐13:00 13:00-‐14:45 14:50-‐15:30 15:30-‐16:00 16:00-‐16:30 16:30-‐17:45 18:00-‐19:00
Title Fermentation basics: important fermentation variables and mode of operation of bioreactors Coffee Fermentation basics: important fermentation variables and mode of operation of bioreactors -‐ continued Lignin acting enzymes Lunch Fermentation of lignocellulosic media: mode of operation and strategies Quantitative evaluation of fermentations of lignocellulose hydrolysate Coffee Lignocellulose hydrolysate fermentation: microbial robustness Exercises Dinner Concluding discussions, questions and sum-‐up
Friday October 30th EXAM and Outlook seminars Time
Title 9:00-‐11:00 Written exam 11:00-‐11:30 Coffee at Volvo foyer, Chalmers Kårhuset
III
Room KS101
Program draft ver. 1.7. Jul 20th, 2015 Friday October 30 th -continued
SEMINARS: HOT TOPICS IN INDUSTRIAL BIOTECHNOLOGY -‐Scaniasalen, Chalmers Kårhuset-‐ Perspectives, challenges and trends towards biorefineries and a new 11:30-‐12:00 bioeconomy. Lisbeth Olsson Chalmers University of Technology; Gothenburg, Sweden
12:00-‐13:00 Lunch at Restaurant “Hyllan”, Chalmers Kårhuset
Tentative title: “From Micro Drive to Lipo Drive: development of biorefinery 13:15-‐13:45 concepts at the Swedish University of Agricultural Sciences”
Mats Sandgren Swedish University of Agricultural Sciences, Uppsala, Sweden
13:45-‐14:15 TBA 14:15-‐14:45 Coffee
Tentative title: “Development of Microbial Cell Factories for Lignocellulosic 14:45-‐15:15 Technologies”
Arthur L. Kruckeberg Industrial BioSciences Technology Team, DuPont Corporation, Wilmington DE USA.
15:15-‐16:00 TBA 16:00-‐ Course evaluation and concluding remarks
Notes 1) N. refers to “Subject Number” in the course literature list 2) TBA: to be announced
Teachers:
Chalmers University of Technology; Gothenburg, Sweden CC: Christel Cederberg; CJF-‐Carl Johan Franzén; DM: David Moreno ; EA-‐Eva Albers; JL: Johan Larsbrink; JVV-‐ Jenny Veide Vilg; KSJ: Katja Salomon Johansen; LO-‐Lisbeth Olsson; MB-‐Maurizio Bettiga; Lund University; Lund, Sweden MG-‐Mats Galbe. University of Helsinki; Helsinki, Finland KH-‐Kristiina Hildén Royal Institute of Technology, Stockholm, Sweden FVD: Francisco Xavier Vilaplana Domingo Novozymes A/S Bagsvaerd, Denmark KBK: Kristian Bertel Rømer Mørkeberg Krogh Evolva A/S CCV: Carlos Casado Vázquez
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Program draft ver. 1.7. Jul 20th, 2015
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